⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701513 | 1.00 | ALDH1A1 (1.00) | — | |
| SCHEMBL17976 | 1.00 | — | — | |
| SCHEMBL117455 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL11774408 | 0.96 | — | — | |
| Water SCHEMBL501966 | 0.96 | ALDH1A1 (0.93) | — | |
| SCHEMBL9786453 | 0.96 | — | — | |
| SCHEMBL15662728 | 0.96 | — | — | |
| Hydroxyl Radical SCHEMBL16714478 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL5581941 | 0.96 | — | — | |
| Phosphine SCHEMBL10954022 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2215 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214938-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)-METHANOL | MERCK SHARP & DOHME LLC (US) | 2025-07-03 | — | — | US | claimed |
| WO-2025131066-A1 | AN IMPROVED PROCESS FOR PRODUCING L-CARNITINE | HUBEI XUJIE PHARMACEUTICAL CO., LTD (CN) | 2025-06-26 | — | — | WO | claimed |
| CN-115894503-B | Preparation method of azacyclopentane derivative | 合肥诺全医药有限公司 | 2025-06-13 | — | — | CN | claimed |
| US-12312320-B2 | Method for synthesizing n-substituted phenyl-5-hydroxymethyl-2-oxazolidinone | HANGZHOU DIKE TECHNOLOGIES CO., LTD. (CN) | 2025-05-27 | — | — | US | claimed |
| CN-120004761-A | Preparation method and system of L-carbonitrile | 湖北远大生命科学与技术有限责任公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119979016-A | High-toughness delayed-curing UV adhesive based on biomass oil and preparation method thereof | 鲁东大学 | 2025-05-13 | — | — | CN | claimed |
| EP-4504704-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)-METHANOL | Merck Sharp & Dohme LLC (US) | 2025-02-12 | — | — | EP | claimed |
| EP-4499619-A1 | SYNTHESIS OF DOPAMINE D3 RECEPTOR SELECTIVE ANTAGONISTS/PARTIAL AGONISTS | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2025-02-05 | — | — | EP | claimed |
| EP-4493550-A1 | PROCESS OF MAKING DERIVATIVES OF SUBSTITUTED MORPHOLINES | Supernus Pharmaceuticals, Inc. (US) | 2025-01-22 | — | — | EP | claimed |
| CN-119137108-A | Synthesis of dopamine D3 receptor selective antagonists/partial agonists | 以秘书处、卫生和人类服务部为代表的美利坚合众国 | 2024-12-13 | — | — | CN | claimed |
| US-20030088114-A1 | Kinetic resolution method | SHASUN PHARMA SOLUTIONS, INC. | 2003-05-08 | — | — | US | claimed |
| US-6248866-B1 | MULTISTEP PROCESS FOR PRODUCTION OF PROTECTED HYPUSINE STARTING FROM PROTECTED, ESTERIFIED LYSINE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2001-06-19 | — | — | US | claimed |
| EP-1032411-A1 | HYPUSINE REAGENT FOR PEPTIDE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| US-5973113-A | Hypusine reagent for peptide synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-10-26 | — | — | US | claimed |
| WO-1999022757-A1 | HYPUSINE REAGENT FOR PEPTIDE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-05-14 | — | — | WO | claimed |
| EP-0629617-B1 | Heteroatom-bearing ligands and metal complexes thereof | BRACCO INT BV (NL) | 1998-04-29 | — | — | EP | claimed |
| US-5741912-A | DIAGNOSIS, THERAPY | BRACCO INTERNATIONAL B.V. | 1998-04-21 | — | — | US | claimed |
| EP-0629617-A1 | Heteroatom-bearing ligands and metal complexes thereof | BRACCO International B.V. (NL) | 1994-12-21 | — | — | EP | claimed |
| US-5177007-A | Alcaligenes | DAISO CO., LTD. (JP) | 1993-01-05 | — | — | US | claimed |
| EP-0242265-B1 | 1,5-BENZOTHIAZEPINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | SYNTHELABO (FR) | 1991-05-29 | — | — | EP | claimed |