Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.93 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL29802904 | 1.00 | — | — | |
| SCHEMBL3701513 | 0.96 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRTP53HBB | |
| SCHEMBL117455 | 0.96 | — | — | |
| SCHEMBL118159 | 0.96 | — | — | |
| SCHEMBL31018802 | 0.96 | — | — | |
| SCHEMBL17976 | 0.96 | — | — | |
| Hydroxyl Radical SCHEMBL16714478 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL3422900 | 0.93 | — | — | |
| SCHEMBL15662728 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL5581941 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112992-A2 | SEALANT MATERIAL | ZEPHYROS, INC. (US) | 2008-09-18 | — | — | WO | claimed |
| US-20070088138-A1 | EPOXY/ELASTOMER ADDUCT, METHOD OF FORMING SAME AND MATERIALS AND ARTICLES FORMED THEREWITH | L&L PRODUCTS, INC. (US) | 2007-04-19 | — | — | US | claimed |
| EP-1599527-A2 | EPOXY/ELASTOMER ADDUCT, METHOD OF FORMING SAME AND MATERIALS AND ARTICLES FORMED THEREWITH | L & L Products, Inc. (US) | 2005-11-30 | — | — | EP | claimed |
| US-20040204551-A1 | Epoxy/elastomer adduct, method of forming same and materials and articles formed therewith | L&L PRODUCTS, INC. | 2004-10-14 | — | — | US | claimed |
| WO-2004078853-A2 | EPOXY/ELASTOMER ADDUCT, METHOD OF FORMING SAME AND MATERIALS AND ARTICLES FORMED THEREWITH | L & L PRODUCTS, INC. (US) | 2004-09-16 | — | — | WO | claimed |
| US-6323264-B1 | EPOXY RESIN OF BISPHENOL-EPICHLOROHYDRIN COPOLYMER WITH DIGLYCIDYLANILINE COMPOUND, STRONTIUM CHROMATE, GLASS AND POLYTETRAFLUOROETHYLENE | TURBINE CONTROLS, INC. | 2001-11-27 | — | — | US | claimed |
| US-6090869-A | Self-lubricating coating composition of epoxy resins, polytetrafluoroethylene, MoS2 and mica | TURBINE CONTROLS, INC. (US) | 2000-07-18 | — | — | US | claimed |
| US-3933425-A | Method of cleaning textiles | HENKEL & CIE GMBH (DT) | 1976-01-20 | — | — | US | claimed |
| EP-3807337-B1 | TOUGHENED EPOXY COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-113910724-B | Discontinuous net structure | 泽菲罗斯有限公司 | 2024-06-11 | — | — | CN | disclosed |
| US-20240150618-A1 | Seal Coated Devices | ZEPHYROS, INC. | 2024-05-09 | — | — | US | disclosed |
| US-20240140537-A1 | Reinforcement Devices | ZEPHYROS, INC. | 2024-05-02 | — | — | US | disclosed |
| CN-115947702-B | Preparation method of octyl glycidyl ether | 江苏扬农锦湖化工有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20240093069-A1 | Activatable Polymer Composition Comprising At Least Two Carboxylic Acids as Blowing Agent | ZEPHYROS, INC. | 2024-03-21 | — | — | US | disclosed |
| US-4438178-A | COATED WITH EPICHLOROHYDRIN ETHER OR ESTER | FIBER INDUSTRIES, INC. (US) | 1984-03-20 | — | — | US | disclosed |
| US-4438178-A | COATED WITH EPICHLOROHYDRIN ETHER OR ESTER | FIBER INDUSTRIES, INC. (US) | 1984-03-20 | — | — | US | disclosed |
| US-4139478-A | Polychlorohydrin ethers of tris-(hydroxymethyl)-aminomethane in association with polyglycol diamines | SANDOZ LTD. (CH) | 1979-02-13 | — | — | US | disclosed |
| US-4059631-A | Polychlorohydrin ethers of tris-(hydroxymethyl)-aminomethane | SANDOZ LTD. (CH) | 1977-11-22 | — | — | US | disclosed |
| US-3987231-A | METHOD OF ANTISTATICALLY TREATING FIBROUS MATERIALS | SANDOZ LTD. (CH) | 1976-10-19 | — | — | US | disclosed |
| US-3933425-A | Method of cleaning textiles | HENKEL & CIE GMBH (DT) | 1976-01-20 | — | — | US | disclosed |