Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816241 | 0.90 | ACACB (0.37) | MAPTCYP1A2CYP2C19RECQLCTSA | |
| SCHEMBL11812772 | 0.85 | MAPT (0.45) | MAPTCYP1A2CYP2C19RECQLCTSA | |
| SCHEMBL11810268 | 0.83 | CYP1A2 (0.44) | MAPTCYP1A2CYP2C19RECQLCTSA | |
| SCHEMBL11817197 | 0.80 | CYP4F2 (0.40) | MAPTCYP1A2CYP2C19RECQLPOLB | |
| SCHEMBL11812363 | 0.75 | MAPT (0.43) | MAPTCYP1A2CYP2C19RECQLCTSA | |
| SCHEMBL11816255 | 0.73 | CCNC (0.38) | MEN1KMT2AALDH1A1MAPK8MAPK10 | |
| SCHEMBL11817548 | 0.73 | ACACB (0.42) | CTSAMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11834922 | 0.71 | MAPK8 (0.40) | CTSAMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11814009 | 0.70 | PTGS1 (0.49) | CTSAMEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL27993659 | 0.67 | TSHR (0.48) | POLBL3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994908-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | disclosed |