Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 2/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | ACACA | Q13085 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813994 | 0.87 | KDM4E (0.51) | LIPEP2RX3ACACBACACAMEN1 | |
| SCHEMBL11410948 | 0.87 | PTGS1 (0.55) | HRH3LIPEACACBACACA | |
| SCHEMBL11813582 | 0.84 | HRH3 (0.54) | HRH3LIPEACACBACACAPTGER4 | |
| SCHEMBL11815648 | 0.83 | PTGS2 (0.60) | ACACBACACAAKR1C3AKR1C2 | |
| SCHEMBL11822740 | 0.82 | HRH3 (0.45) | HRH3LIPEP2RX3ACACBACACA | |
| SCHEMBL11810555 | 0.81 | TDP1 (0.49) | ACACBACACAMEN1KMT2ASCN9A | |
| SCHEMBL11838821 | 0.81 | ACACB (0.44) | ACACBACACAAKR1C3AKR1C2 | |
| SCHEMBL11813412 | 0.80 | PTGS1 (0.47) | P2RX3MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL11818099 | 0.78 | HRH3 (0.53) | HRH3ACACBMEN1KMT2APTGER4 | |
| SCHEMBL8683717 | 0.78 | LIPE (0.54) | HRH3LIPEP2RX3ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940403-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1976-02-24 | — | — | US | claimed |