Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812543 | 1.00 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL11817596 | 0.92 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL11068656 | 0.80 | ALDH1A1 (0.76) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL15966835 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL15966796 | 0.79 | ALDH1A1 (0.83) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL10805347 | 0.79 | ALDH1A1 (0.74) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL10805754 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL11818525 | 0.77 | KDM5A (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL11814916 | 0.77 | KDM5A (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL10807501 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |