Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812543 | 0.92 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNARECQLHTT | |
| SCHEMBL11816514 | 0.92 | ALDH1A1 (0.65) | KDM4EALDH1A1LMNARECQLHTT | |
| SCHEMBL15966860 | 0.79 | ALDH1A1 (0.82) | KDM4EALDH1A1LMNARECQLHTT | |
| SCHEMBL11826450 | 0.79 | MEN1 (0.53) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11817456 | 0.77 | KDM5A (0.55) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2383886 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1LMNARECQLHTT | |
| SCHEMBL25942765 | 0.74 | TSHR (0.44) | KDM4EALDH1A1LMNAHTTMEN1 | |
| SCHEMBL11814916 | 0.74 | KDM5A (0.52) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL25942837 | 0.74 | TSHR (0.44) | KDM4EALDH1A1LMNAHTTMEN1 | |
| SCHEMBL11818525 | 0.74 | KDM5A (0.52) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |