SCHEMBL11816622

SCHEMBL11816622

NC1=NC2CCCCCCC2O1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 10/20 0.40
NOS2 P35228 10/20 0.40
NOS3 P29474 9/20 0.40
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11812537 1.00 NOS1 (0.40) NOS1NOS2NOS3ACHE
SCHEMBL9416567 0.98 NOS1 (0.38) NOS1NOS2NOS3ACHE
SCHEMBL9416568 0.98 NOS1 (0.38) NOS1NOS2NOS3ACHE
SCHEMBL9416566 0.98 NOS1 (0.38) NOS1NOS2NOS3ACHE
SCHEMBL11818202 0.93
SCHEMBL13082564 0.74 NOS1 (0.32) NOS1NOS2NOS3
SCHEMBL15935488 0.74 NOS1 (0.32) NOS1NOS2NOS3
SCHEMBL3411717 0.71 NOS3 (0.37) NOS1NOS2NOS3
SCHEMBL6212286 0.71 NOS1 (0.31) NOS1NOS2NOS3
SCHEMBL7080959 0.71 NOS1 (0.31) NOS1NOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3225618-B1 BICYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2020-05-06 EP disclosed
US-3931214-A 2-Amino-2-oxazolines and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed