SCHEMBL11816645

SCHEMBL11816645

[K]C(c1ccccc1)(c1ccccc1)c1ccccc1.[Na]C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 2/20 0.33
KIF11 P52732 1/20 0.32
CYP1A2 P05177 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP3A4 P08684 2/20 0.30
PTPN1 P18031 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297878 0.86 KCNN4 (0.47) KCNN4ALDH1A1TSHRMAPK1KIF11
SCHEMBL298364 0.86 KCNN4 (0.47) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL3889625 0.83 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
Methyl Alcohol SCHEMBL28881402 0.78 ALDH1A1 (0.44) KCNN4ALDH1A1TSHRMAPK1CYP1A2
Naphthalene SCHEMBL11519928 0.76 CYP2A6 (0.44) KCNN4ALDH1A1TSHRMAPK1CYP1A2
Sulfurous Acid SCHEMBL27859602 0.72 CYP1A2 (0.44) KCNN4ALDH1A1TSHRMAPK1CYP1A2
Ether SCHEMBL27935725 0.69 KCNN4 (0.40) KCNN4ALDH1A1TSHRMAPK1KIF11
SCHEMBL5498484 0.67 KCNN4 (0.47) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL8440794 0.67 CA4 (0.54) KIF11
SCHEMBL11439383 0.65 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3965122-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-06-22 US disclosed