SCHEMBL298364

SCHEMBL298364

[Na]C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.47
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.41
CYP1A2 P05177 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ALOX15 P16050 1/20 0.38
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
CYP3A4 P08684 2/20 0.36
PTPN1 P18031 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3889625 0.97 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
Methyl Alcohol SCHEMBL28881402 0.91 ALDH1A1 (0.44) KCNN4ALDH1A1TSHRMAPK1CYP1A2
Naphthalene SCHEMBL11519928 0.88 CYP2A6 (0.44) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL11816645 0.86 KCNN4 (0.38) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL5498484 0.79 KCNN4 (0.47) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL8440794 0.78 CA4 (0.54)
SCHEMBL11439383 0.76 KCNN4 (0.45) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL9245544 0.73 CYP1A2 (0.44) KCNN4ALDH1A1TSHRMAPK1CYP1A2
SCHEMBL3889984 0.73 MAPK1 (0.50) KCNN4ALDH1A1TSHRMAPK1TAAR1
SCHEMBL2125552 0.71 KCNN4 (0.41) KCNN4ALDH1A1TSHRMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473252-B2 Processes for the preparation of deuterated D-serine SUN PHARMACEUTICAL INDUSTRIES, INC. (US) 2025-11-18 US claimed
US-12338326-B2 Polyamides with pendent optical absorbers and related methods XEROX CORPORATION (US) 2025-06-24 US claimed
CN-119977783-A Synthesis method of oxaloacetic acid 上海高准医药有限公司 2025-05-13 CN claimed
US-20250042841-A1 PROCESSES FOR THE PREPARATION OF DEUTERATED D-SERINE SUN PHARMACEUTICAL INDUSTRIES, INC. 2025-02-06 US claimed
CN-118388329-B Tapentadol Process for the preparation of intermediates 江苏海洋大学 2024-11-15 CN claimed
CN-112457487-B Polyamide with overhanging optical absorbers and related methods 施乐公司 2024-10-01 CN claimed
US-12065395-B2 Processes for the preparation of deuterated D-serine SUN PHARMACEUTICAL INDUSTRIES, INC. (US) 2024-08-20 US claimed
CN-118388329-A Preparation method of tapentadol intermediate 江苏海洋大学 2024-07-26 CN claimed
CN-116463159-B Antioxidant additive, preparation method and application thereof 中国石油天然气股份有限公司 2024-07-23 CN claimed
CN-118359540-A Method for producing tolfenpyrad insecticide 新沂市永诚化工有限公司 2024-07-19 CN claimed
EP-0458309-A2 Dicyclopentadiene activation method and polymerization composition NIPPON ZEON CO., LTD. (JP) 1991-11-27 EP claimed
US-4908420-A Hydrogenating, polymerizing unsaturated alkyl chain-containing norbornene containing compound NIPPON OIL COMPANY, LTD. (JP) 1990-03-13 US claimed
EP-0352772-A2 Method for preparing resin having light color NIPPON OIL CO., LTD. (JP) 1990-01-31 EP claimed
US-4891456-A Method for preparing norbornene structure compound NIPPON OIL CO., LTD. (JP) 1990-01-02 US claimed
EP-0298408-A1 Method for preparing norbornene structure compound NIPPON OIL CO. LTD. (JP) 1989-01-11 EP claimed
US-4307232-A Preparation of dialkyl- and diarylphosphonoalkanoic acids and substituted acrylic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-22 US claimed
US-4252925-A HYDROCARBYLMETAL CATALYST TOYO SODA MANUFACTURING CO., LTD. (JP) 1981-02-24 US claimed
US-4247699-A REACTION OF AN ISATOIC ANHYDRIDE WITH MALONONITRILE FOLLOWED BY TREATMENT WITH A STRONG ACID OR BASE PFIZER INC. (US) 1981-01-27 US claimed
US-4031130-A Aliphatic β-keto esters AGFA-GEVAERT, A.G. (DT) 1977-06-21 US claimed
US-4029616-A Polymer composition of ethylenic compounds and pullulan SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473252-B2 Processes for the preparation of deuterated D-serine PSPH, SRR, DHPS KCNN4 4813/4885ALDH1A1 3327/4885TSHR 3758/4885
US-12065395-B2 Processes for the preparation of deuterated D-serine PSPH, SRR, DHPS KCNN4 4813/4885ALDH1A1 3327/4885TSHR 3758/4885
US-20250042841-A1 PROCESSES FOR THE PREPARATION OF DEUTERATED D-SERINE PSPH, SRR, DHPS KCNN4 4813/4885ALDH1A1 3327/4885TSHR 3758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.