Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821360 | 0.85 | CA12 (0.41) | MAPTALDH1A1KDM4ELMNACNR1 | |
| SCHEMBL11818519 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAHSD17B10CASP1 | |
| SCHEMBL734030 | 0.85 | KCNN4 (0.42) | MAPTALDH1A1KDM4ELMNACNR1 | |
| SCHEMBL3519610 | 0.85 | L3MBTL1 (0.45) | MAPTKDM4ELMNACNR1CNR2 | |
| SCHEMBL4431087 | 0.83 | MEN1 (0.45) | MAPTCNR1CNR2HSD17B10CASP1 | |
| SCHEMBL7744791 | 0.82 | HSD17B10 (0.41) | MAPTALDH1A1KDM4ELMNACNR1 | |
| SCHEMBL11066784 | 0.81 | MIF (0.47) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL2873973 | 0.81 | MAPT (0.51) | MAPTALDH1A1PTGS2KMT2APOLB | |
| SCHEMBL16691418 | 0.80 | L3MBTL1 (0.41) | MAPTKDM4ELMNACNR1CNR2 | |
| SCHEMBL6544463 | 0.80 | L3MBTL1 (0.41) | MAPTALDH1A1KDM4ECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979444-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, HYPOTENSIVES | THE UPJOHN COMPANY (US) | 1976-09-07 | — | — | US | disclosed |