Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808295 | 0.83 | NOX1 (0.44) | NOX1BCHEACHEALOX5MEN1 | |
| Benzene SCHEMBL28125613 | 0.82 | ALOX5 (0.54) | NOX1BCHEACHEALOX5MEN1 | |
| SCHEMBL293434 | 0.82 | ALOX5 (0.54) | NOX1BCHEACHEALOX5MEN1 | |
| Flutiazin SCHEMBL29394002 | 0.80 | NOX1 (0.58) | NOX1ALOX5MEN1GAAMAPT | |
| Flutiazin SCHEMBL193601 | 0.80 | NOX1 (0.58) | NOX1ALOX5MEN1GAAMAPT | |
| Flutiazin SCHEMBL11811863 | 0.79 | NOX1 (0.57) | NOX1ALOX5MEN1GAAMAPT | |
| SCHEMBL11812879 | 0.78 | NOX1 (0.41) | NOX1ALOX5MEN1GAAMAPT | |
| SCHEMBL27861131 | 0.77 | NOX1 (0.61) | NOX1BCHEACHEMEN1GAA | |
| SCHEMBL11817545 | 0.75 | SNCA (0.45) | NOX1BCHEALOX5MEN1GAA | |
| SCHEMBL1509893 | 0.75 | NOX1 (0.84) | NOX1BCHEACHEMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962438-A | Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones | SMITHKLINE CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |