Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.35 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYBB | P04839 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293434 | 0.82 | ALOX5 (0.54) | SNCAALOX5KDM4ELIG1BCHE | |
| Benzene SCHEMBL28125613 | 0.82 | ALOX5 (0.54) | SNCAALOX5KDM4ELIG1BCHE | |
| SCHEMBL11823962 | 0.81 | NOX1 (0.49) | ALOX5KDM4ENOX1MEN1KMT2A | |
| SCHEMBL11811978 | 0.80 | NOX1 (0.58) | SNCAKDM4EAKR1C3BCHENOX1 | |
| SCHEMBL11822439 | 0.79 | SNCA (0.61) | SNCAAKR1C3NOX1GAAMAPT | |
| SCHEMBL11817565 | 0.77 | MEN1 (0.45) | SNCAKDM4ENOX1MEN1KMT2A | |
| SCHEMBL17996072 | 0.77 | SNCA (0.46) | SNCAKDM4EBCHESLC6A3NOX1 | |
| SCHEMBL20424966 | 0.77 | SNCA (0.46) | SNCABCHESLC6A3NOX1MEN1 | |
| SCHEMBL11818316 | 0.75 | NOX1 (0.55) | SNCAALOX5LIG1BCHENOX1 | |
| SCHEMBL11808295 | 0.75 | NOX1 (0.44) | SNCAALOX5KDM4ELIG1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962438-A | Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones | SMITHKLINE CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |