Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817308 | 0.83 | SIGMAR1 (0.56) | SIGMAR1OPRK1 | |
| SCHEMBL12716235 | 0.73 | SIGMAR1 (0.73) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL12267534 | 0.73 | SIGMAR1 (0.73) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL12324824 | 0.73 | SIGMAR1 (0.73) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL15706497 | 0.73 | SIGMAR1 (0.58) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL18623622 | 0.72 | SIGMAR1 (0.56) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL18623620 | 0.72 | SIGMAR1 (0.56) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL15706493 | 0.72 | SIGMAR1 (0.53) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL15706496 | 0.72 | SLC6A2 (0.53) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 | |
| SCHEMBL18623637 | 0.69 | SLC6A2 (0.53) | SIGMAR1SLC6A2GRIN1GRIN2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951984-A | 3-Benzazocine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | claimed |
| US-3951984-A | 3-Benzazocine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |