Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820400 | 0.86 | — | — | |
| SCHEMBL11818119 | 0.84 | GRM2 (0.31) | GRM4CYP2C19CYP1A2TDP1GRM8 | |
| SCHEMBL11818527 | 0.76 | GRM8 (0.35) | GRM4CYP2C19ALDH1A1CYP1A2MEN1 | |
| SCHEMBL11817779 | 0.76 | — | — | |
| SCHEMBL4380991 | 0.76 | CYP2C19 (0.55) | GRM4CYP2C19ALDH1A1CYP1A2MEN1 | |
| SCHEMBL11820427 | 0.76 | — | — | |
| SCHEMBL11815474 | 0.76 | GRM4 (0.31) | GRM4CYP2C19ALDH1A1CYP1A2MEN1 | |
| SCHEMBL7739044 | 0.72 | SLC6A4 (0.45) | GRM4CYP2C19ALDH1A1CYP1A2MEN1 | |
| SCHEMBL11819887 | 0.72 | GRM4 (0.33) | GRM4CYP2C19CYP1A2TDP1GRM8 | |
| SCHEMBL11473353 | 0.70 | ARG1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954730-A | ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |