SCHEMBL7739044

SCHEMBL7739044

O=C(O)C1CC(C(=O)O)CC(Cl)(C(=O)O)C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.45
CYP2C19 P33261 5/20 0.44
CYP1A2 P05177 4/20 0.43
ALOX15 P16050 3/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
APLNR P35414 1/20 0.41
GRM4 Q14833 8/20 0.38
GRM2 Q14416 5/20 0.38
GRM6 O15303 4/20 0.38
GRM5 P41594 4/20 0.38
GRM3 Q14832 3/20 0.38
GRM1 Q13255 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
GRM8 O00222 2/20 0.38
LMNA P02545 1/20 0.38
MTOR P42345 1/20 0.38
PLCB1 Q9NQ66 1/20 0.38
TSHR P16473 1/20 0.38
CYP2D6 P10635 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4380991 0.90 CYP2C19 (0.55) SLC6A4CYP2C19CYP1A2ALOX15ALDH1A1
SCHEMBL4372279 0.77 GRM4 (0.53) SLC6A4CYP2C19CYP1A2ALOX15ALDH1A1
SCHEMBL4381001 0.74 CYP1A2 (0.46) SLC6A4CYP2C19CYP1A2ALOX15ALDH1A1
SCHEMBL11820400 0.74
SCHEMBL11819086 0.72 GRM4 (0.32) CYP2C19CYP1A2ALOX15ALDH1A1KDM4E
SCHEMBL895276 0.71 GRM2 (0.47) SLC6A4CYP2C19CYP1A2ALOX15ALDH1A1
SCHEMBL9088184 0.71 SLC6A4 (0.55) SLC6A4CYP2C19CYP1A2ALOX15ALDH1A1
SCHEMBL11817779 0.70
SCHEMBL11818527 0.70 GRM8 (0.35) CYP2C19CYP1A2ALOX15ALDH1A1KDM4E
SCHEMBL11820427 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024174089-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR 万华化学集团股份有限公司 2024-08-29 WO claimed
CN-112225891-B Preparation method of long-chain star branching agent and high-fluidity high-crystallization long-carbon-chain star polyamide 惠生(中国)投资有限公司 2023-02-07 CN claimed
CN-114045161-A Method for improving plugging range of polymer water plugging interlayer at gas-water interface 西南石油大学 2022-02-15 CN claimed
WO-2024174089-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR 万华化学集团股份有限公司 2024-08-29 WO disclosed
CN-112225891-B Preparation method of long-chain star branching agent and high-fluidity high-crystallization long-carbon-chain star polyamide 惠生(中国)投资有限公司 2023-02-07 CN disclosed
CN-111841343-B Asymmetric polyamide nano-film and preparation method thereof 河南师范大学 2022-04-15 CN disclosed
CN-108325389-B Azlactone-based polyamide membrane and preparation method thereof 中国石油大学(华东) 2021-07-27 CN disclosed
CN-111841343-A Asymmetric polyamide nano-film and preparation method thereof 河南师范大学 2020-10-30 CN disclosed
CN-106986989-B Preparation method of polyamide hollow nano-microspheres 天津工业大学 2020-10-27 CN disclosed
US-10780401-B2 Highly selective alicyclic polyamide nanofiltration membrane and making method thereof CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) 2020-09-22 US disclosed
US-20180326362-A1 Highly selective alicyclic polyamide nanofiltration membrane and making method thereof CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) 2018-11-15 US disclosed
US-6417339-B1 CORE, SPACERS DEUTSCHES KREBSFORSCHUNGZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 2002-07-09 US disclosed
US-5510527-A Acid chloride NITTO DENKO CORPORATION (JP) 1996-04-23 US disclosed
US-5336409-A Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1994-08-09 US disclosed
EP-0556569-A2 Composite reverse osmosis membrane and novel acid chloride NITTO DENKO CORPORATION (JP) 1993-08-25 EP disclosed
US-5147553-A Separation of fluid mixture IONICS, INCORPORATED (US) 1992-09-15 US disclosed