Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815689 | 0.82 | CNR2 (0.50) | DRD4CNR2MEN1KMT2ACNR1 | |
| SCHEMBL11816682 | 0.71 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL11716511 | 0.69 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL11627150 | 0.65 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL1147448 | 0.62 | SIGMAR1 (0.50) | DRD4MEN1KMT2ADRD3ACHE | |
| SCHEMBL12002187 | 0.62 | SIGMAR1 (0.50) | DRD4MEN1KMT2AACHELMNA | |
| SCHEMBL5621315 | 0.61 | SIGMAR1 (0.57) | DRD4MEN1KMT2AACHELMNA | |
| SCHEMBL27645025 | 0.61 | DRD4 (0.56) | DRD4MEN1KMT2AGAADRD3 | |
| SCHEMBL10142868 | 0.60 | SIGMAR1 (0.55) | DRD4MEN1KMT2ADRD3ACHE | |
| SCHEMBL6710633 | 0.60 | DRD2 (0.54) | DRD4GAADRD2DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962448-A | CNS DEPRESSANTS, VETERINARY | SMITHKLINE CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |