Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814079 | 0.86 | TP53 (0.64) | TP53MAPT | |
| SCHEMBL11818781 | 0.83 | TP53 (0.54) | TP53MEN1KMT2ALMNAMAPT | |
| SCHEMBL16298245 | 0.81 | MRGPRX4 (0.66) | NR4A2MRGPRX4MEN1KMT2AMAPT | |
| SCHEMBL11820512 | 0.81 | POLB (0.46) | NR4A2TP53MEN1KMT2ALMNA | |
| SCHEMBL11818098 | 0.81 | NR4A2 (0.44) | NR4A2MRGPRX4TP53MEN1KMT2A | |
| SCHEMBL10796106 | 0.79 | MEN1 (0.57) | MEN1KMT2ALMNAMAPTKIF11 | |
| SCHEMBL2721465 | 0.77 | NR4A2 (0.66) | NR4A2MRGPRX4MEN1KMT2AMAPT | |
| SCHEMBL11815247 | 0.77 | MPO (0.56) | MEN1KMT2ALMNAMAPTMPO | |
| SCHEMBL13625639 | 0.77 | PRKCA (0.69) | NR4A2MEN1KMT2ALMNAMAPT | |
| SCHEMBL129366 | 0.75 | TP53 (0.50) | TP53MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |