Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090363 | 0.79 | MAPT (0.43) | GSK3BRAB9ANPC1MAPTHPGD | |
| SCHEMBL11777129 | 0.78 | GSK3B (0.43) | GSK3BRAB9ANPC1MAPTHPGD | |
| SCHEMBL5049650 | 0.77 | PKM (0.45) | GSK3BRAB9ANPC1MAPTHPGD | |
| SCHEMBL6857304 | 0.77 | PTPN2 (0.48) | GSK3BRAB9ANPC1MAPTHPGD | |
| SCHEMBL14218016 | 0.76 | PTPN1 (0.50) | RAB9ANPC1MAPTHPGDTP53 | |
| SCHEMBL12213152 | 0.76 | PTK2 (0.59) | GSK3BRAB9ANPC1MAPTHPGD | |
| SCHEMBL3337813 | 0.74 | PTK2 (0.49) | RAB9ANPC1MAPTHPGDTP53 | |
| SCHEMBL765316 | 0.74 | SMN1; SMN2 (0.56) | GSK3BRAB9ANPC1MAPTHPGD | |
| SCHEMBL6924499 | 0.71 | HDAC3 (0.65) | MAPTTP53L3MBTL1POLBGAA | |
| SCHEMBL7782661 | 0.70 | TP53 (0.49) | RAB9ANPC1MAPTHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3958974-A | Herbicidal N-aryl substituted azetidinones | VELSICOL CHEMICAL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |