Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813745 | 0.92 | LMNA (0.64) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11820183 | 0.92 | LMNA (0.64) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11814228 | 0.87 | KDM4E (0.53) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11815803 | 0.82 | POLB (0.49) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11830597 | 0.82 | KMT2A (0.62) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11820333 | 0.81 | POLB (0.61) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11815260 | 0.81 | LMNA (0.53) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11815520 | 0.80 | CNR2 (0.65) | LMNAHPGDKMT2AMEN1MAPT | |
| SCHEMBL4176910 | 0.79 | LMNA (0.65) | LMNAHPGDKMT2AMEN1POLB | |
| SCHEMBL11817264 | 0.79 | LMNA (0.52) | LMNAHPGDKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |