Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815418 | 0.89 | KDM4E (0.55) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL11820333 | 0.85 | POLB (0.61) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL7057820 | 0.84 | LMNA (0.65) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL9442734 | 0.81 | HSD17B10 (0.63) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL11820183 | 0.81 | LMNA (0.64) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL11820366 | 0.81 | LMNA (0.55) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL11813745 | 0.81 | LMNA (0.64) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL7282582 | 0.80 | LMNA (0.60) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL7298147 | 0.80 | LMNA (0.60) | LMNAHPGDPOLBKDM4EALDH1A1 | |
| SCHEMBL11818406 | 0.74 | ALDH1A1 (0.51) | LMNAPOLBKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |