Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826406 | 0.89 | DRD2 (0.55) | DRD2HTR2CHTR2ASIGMAR1 | |
| SCHEMBL11822536 | 0.86 | DRD2 (0.57) | DRD2SIGMAR1 | |
| SCHEMBL11821412 | 0.85 | DRD2 (0.57) | DRD2SIGMAR1 | |
| SCHEMBL11820579 | 0.85 | DRD2 (0.56) | DRD2HTR2CHTR2ASIGMAR1 | |
| SCHEMBL11831827 | 0.84 | DRD2 (0.56) | DRD2SIGMAR1 | |
| SCHEMBL11824725 | 0.83 | DRD2 (0.57) | DRD2HTR2CHTR2ASIGMAR1MEN1 | |
| SCHEMBL11821144 | 0.82 | SIGMAR1 (0.48) | HTR2CHTR2ASIGMAR1MEN1KMT2A | |
| SCHEMBL11825932 | 0.82 | DRD2 (0.44) | DRD2HTR2CHTR2AHTR2B | |
| SCHEMBL11822276 | 0.82 | DRD2 (0.44) | DRD2HTR2CHTR2AHTR2BMEN1 | |
| SCHEMBL11821896 | 0.82 | HRH3 (0.43) | DRD2HTR2CHTR2ASIGMAR1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980797-A | Hexahydro-diazepino-indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-09-14 | — | — | US | claimed |
| US-3980797-A | Hexahydro-diazepino-indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-09-14 | — | — | US | disclosed |