Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11821676 | 1.00 | HCAR2 (0.43) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11831427 | 0.85 | MAOB (0.47) | HCAR2MAOBBRS3MMEITGB1 | |
| Ethane SCHEMBL11827755 | 0.83 | MAOB (0.48) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11823509 | 0.83 | MAOB (0.45) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11829318 | 0.82 | MAOB (0.50) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11829300 | 0.82 | MAOB (0.49) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11827316 | 0.82 | MAOB (0.44) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11823437 | 0.81 | MAOB (0.46) | HCAR2MAOBBRS3MMEITGB1 | |
| SCHEMBL11830406 | 0.81 | HCAR2 (0.44) | HCAR2MAOBBRS3MMEPPARG | |
| Alcohol SCHEMBL11826938 | 0.81 | MAOB (0.46) | HCAR2MAOBBRS3MMEITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |