Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL11827755 | 0.98 | MAOB (0.48) | MAOBHCAR2MMEBRS3SCN9A | |
| SCHEMBL11834365 | 0.90 | MAOB (0.48) | MAOBHCAR2MMEBRS3SCN9A | |
| Alcohol SCHEMBL11826938 | 0.88 | MAOB (0.46) | MAOBHCAR2MMEBRS3SCN9A | |
| SCHEMBL11831427 | 0.88 | MAOB (0.47) | MAOBHCAR2MMEBRS3ITGB1 | |
| SCHEMBL11823437 | 0.86 | MAOB (0.46) | MAOBHCAR2MMEBRS3ITGB1 | |
| SCHEMBL11823509 | 0.85 | MAOB (0.45) | MAOBHCAR2MMEBRS3ITGB1 | |
| SCHEMBL11832469 | 0.85 | MMP12 (0.51) | MMEFFAR1MMP2MMP9MMP12 | |
| SCHEMBL11829300 | 0.85 | MAOB (0.49) | MAOBHCAR2MMEBRS3ITGB1 | |
| SCHEMBL11827316 | 0.84 | MAOB (0.44) | MAOBHCAR2MMEBRS3ITGB1 | |
| SCHEMBL11830406 | 0.83 | HCAR2 (0.44) | MAOBHCAR2MMEBRS3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |