Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819840 | 1.00 | VCAM1 (0.62) | VCAM1LMNAALDH1A1TSHRGAA | |
| SCHEMBL11818879 | 1.00 | VCAM1 (0.62) | VCAM1LMNAALDH1A1TSHRGAA | |
| SCHEMBL11826011 | 1.00 | VCAM1 (0.62) | VCAM1LMNAALDH1A1TSHRGAA | |
| SCHEMBL4717293 | 0.90 | ALDH1A1 (0.61) | VCAM1LMNAALDH1A1TSHRGAA | |
| SCHEMBL7335509 | 0.85 | ALDH1A1 (0.72) | VCAM1LMNAALDH1A1TSHRGAA | |
| SCHEMBL11816670 | 0.84 | S1PR3 (0.50) | VCAM1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11817543 | 0.84 | S1PR3 (0.50) | VCAM1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11828911 | 0.82 | VCAM1 (0.49) | VCAM1MEN1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL11820143 | 0.82 | VCAM1 (0.49) | VCAM1MEN1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL11173512 | 0.81 | KMT2A (0.54) | VCAM1LMNAALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |