Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | GOT1 | P17174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833039 | 0.79 | GAA (0.41) | GAAMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL11831985 | 0.77 | TDP1 (0.40) | GAAALDH1A1NR4A2KAT2BTRPM8 | |
| SCHEMBL11824586 | 0.75 | GAA (0.37) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL9907139 | 0.74 | GAA (0.39) | GAAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL1189327 | 0.71 | MAPT (0.43) | GAAMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL11824272 | 0.70 | CYP2C19 (0.42) | GAAMAPTALDH1A1TDP1KDM4E | |
| SCHEMBL11818709 | 0.70 | TLR8 (0.39) | GAAMAPTALDH1A1NR4A2KDM4E | |
| SCHEMBL11833599 | 0.70 | MAPT (0.40) | GAAMAPTALDH1A1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL11825997 | 0.69 | TLR8 (0.38) | GAAMAPTALDH1A1NR4A2KDM4E | |
| SCHEMBL11823540 | 0.69 | GAA (0.33) | GAAMAPTALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |