Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425666 | 0.80 | TDP1 (0.38) | TDP1KAT2BNR4A2GAASYK | |
| SCHEMBL11822026 | 0.77 | ALDH1A1 (0.33) | TDP1KAT2BNR4A2GAAALDH1A1 | |
| SCHEMBL11822452 | 0.77 | GAA (0.37) | TDP1KAT2BNR4A2GAALRRK2 | |
| Hydrochloric Acid SCHEMBL11831996 | 0.76 | GOT1 (0.33) | TDP1KAT2BNR4A2GAAALDH1A1 | |
| SCHEMBL2490312 | 0.76 | TDP1 (0.44) | TDP1KAT2BALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL23338555 | 0.75 | TDP1 (0.48) | TDP1GAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19021178 | 0.73 | SYK (0.58) | LRRK2SYK | |
| SCHEMBL10510012 | 0.71 | TDP1 (0.50) | TDP1GAAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL3448310 | 0.71 | TDP1 (0.40) | TDP1ALDH1A1RAB9AL3MBTL1SYK | |
| SCHEMBL31589301 | 0.71 | TDP1 (0.40) | TDP1ALDH1A1RAB9AL3MBTL1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978057-A | HYPOTENSIVE AGENTS | SANDOZ, INC. (US) | 1976-08-31 | — | — | US | disclosed |