Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823884 | 0.83 | MAPT (0.42) | MAPTKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11824715 | 0.81 | MAPT (0.41) | MAPTKMT2ASMN1; SMN2KDM4EKCNQ3 | |
| SCHEMBL11823112 | 0.81 | MAPT (0.41) | MAPTKMT2ASMN1; SMN2KDM4EKCNQ3 | |
| SCHEMBL11826962 | 0.76 | MAPT (0.44) | MAPTKMT2ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL11825633 | 0.74 | MGMT (0.36) | MAPTKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11818955 | 0.72 | MAPT (0.46) | MAPTKMT2ASMN1; SMN2KDM4EKCNQ3 | |
| SCHEMBL11826064 | 0.71 | MAPT (0.54) | MAPTKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11828426 | 0.70 | MAPT (0.53) | MAPTKMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11826745 | 0.70 | L3MBTL1 (0.42) | MAPTKMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11825201 | 0.69 | KCNQ3 (0.39) | MAPTKMT2ASMN1; SMN2KDM4EKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |