Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828426 | 0.87 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11833128 | 0.87 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11828195 | 0.87 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11824655 | 0.77 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11822505 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11822497 | 0.76 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11823884 | 0.76 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL11822386 | 0.73 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11824044 | 0.73 | MEN1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11860067 | 0.73 | MEN1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |