SCHEMBL11822650

SCHEMBL11822650

CN(C)C(=O)C1CCCc2c1c1ccccc1n2Cc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.67
TSPO P30536 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5764974 0.87 HTR6 (0.72) HTR6
SCHEMBL11828582 0.87 HTR6 (0.60) HTR6TSPO
SCHEMBL29966259 0.85 HTR6 (0.58) HTR6TSPO
SCHEMBL4263164 0.82 HTR6 (0.55) HTR6TSPO
SCHEMBL11823623 0.82 HTR6 (0.55) HTR6TSPO
SCHEMBL11823611 0.82 HTR6 (0.55) HTR6TSPO
SCHEMBL11827808 0.81 HTR6 (0.54) HTR6TSPO
SCHEMBL415392 0.81 TSPO (0.70) TSPO
SCHEMBL15101782 0.81 TSPO (0.70) TSPO
SCHEMBL414227 0.81 TSPO (0.61) HTR6TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3979391-A 1,2,3,4-Tetrahydrocarbazoles STERLING DRUG INC. (US) 1976-09-07 US disclosed
US-3939177-A 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles STERLING DRUG INC. (US) 1976-02-17 US disclosed