Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | CASP5 | P51878 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CASP4 | P49662 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823380 | 1.00 | PRKDC (0.38) | PRKDCMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL16094661 | 0.79 | MAPT (0.57) | MAPTKDM4EALDH1A1KMT2ACYP1A2 | |
| Aethimidinum SCHEMBL29352989 | 0.79 | CASP1 (0.50) | MAPTCASP1CASP5KMT2ACASP4 | |
| SCHEMBL11822255 | 0.77 | POLB (0.39) | KDM4EALDH1A1L3MBTL1KMT2ACYP1A2 | |
| SCHEMBL11824044 | 0.74 | MEN1 (0.50) | MAPTKDM4EALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11825280 | 0.73 | CYP1A2 (0.44) | PRKDCMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2772556 | 0.72 | CASP1 (0.61) | MAPTCASP1CASP5KMT2ACASP4 | |
| SCHEMBL2773410 | 0.72 | CASP1 (0.56) | MAPTCASP1CASP5KMT2ACASP4 | |
| SCHEMBL9202114 | 0.71 | HRH4 (0.59) | HRH4 | |
| SCHEMBL11835633 | 0.71 | NOS2 (0.36) | PRKDCKDM4EALDH1A1CASP1CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |