Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824346 | 0.79 | — | — | |
| SCHEMBL28197543 | 0.77 | CHRM2 (0.38) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6646476 | 0.74 | CHRM2 (0.33) | ALDH1A1TSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL6648703 | 0.74 | SYK (0.40) | CHRM2CHRM1CHRM3 | |
| SCHEMBL10916885 | 0.73 | TDP1 (0.50) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL14527076 | 0.71 | ADRA1A (0.53) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL6647404 | 0.70 | ACACB (0.32) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9294105 | 0.70 | DRD4 (0.46) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL9534864 | 0.69 | ALDH1A1 (0.46) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL14060929 | 0.68 | TDP1 (0.53) | TDP1ALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3982010-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3982010-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3896139-A | PROCESS FOR PREPARING 3-(4-OR-5-AZIDOCARBONYLTHIAZOL-2-OXY)-PROPANEDIOL-1,2-ACETONIDES | SYNTEX INC | 1975-07-22 | — | — | US | disclosed |