Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581464 | 0.82 | HSD11B1 (0.54) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL2648128 | 0.82 | HSD11B1 (0.54) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8744712 | 0.80 | HSD11B1 (0.53) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8420333 | 0.80 | RAB9A (0.56) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL30016132 | 0.80 | GSK3B (0.59) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| Methyl Alcohol SCHEMBL28304029 | 0.80 | HSD11B1 (0.53) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1434608 | 0.80 | GSK3B (0.59) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5569924 | 0.78 | MEN1 (0.51) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9352393 | 0.78 | HSD11B1 (0.55) | HSD11B1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL9274995 | 0.78 | RAB9A (0.53) | HSD11B1NPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |