Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816111 | 0.85 | TP53 (0.43) | KMT2AMEN1MAPTTDP1CYP1A2 | |
| SCHEMBL11818420 | 0.84 | TAS2R14 (0.43) | KMT2AMEN1TAS2R14 | |
| SCHEMBL11816372 | 0.81 | TP53 (0.48) | KMT2AMEN1MAPTTDP1GAA | |
| SCHEMBL11815276 | 0.80 | KMT2A (0.51) | KMT2AMEN1MAPTTDP1CYP1A2 | |
| SCHEMBL11820864 | 0.77 | TAS2R14 (0.44) | KMT2AALDH1A1SMN1; SMN2TAS2R14 | |
| SCHEMBL11815267 | 0.76 | KMT2A (0.47) | KMT2AMEN1MAPTTDP1CYP1A2 | |
| SCHEMBL11820449 | 0.76 | MAPT (0.48) | KMT2AMEN1MAPTTDP1CYP1A2 | |
| SCHEMBL11815303 | 0.74 | CA12 (0.48) | MAPTALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL30958878 | 0.73 | IDO1 (0.46) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL11823158 | 0.73 | POLB (0.47) | KMT2AMEN1MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |