Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824959 | 0.85 | KMT2A (0.46) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11816372 | 0.84 | TP53 (0.48) | TP53ATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11823158 | 0.76 | POLB (0.47) | TP53ALDH1A1MAPTSMN1; SMN2ALOX5 | |
| SCHEMBL11818774 | 0.75 | ALDH1A1 (0.46) | TP53ATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11815968 | 0.74 | MAPT (0.45) | TP53ATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11816786 | 0.73 | TDP1 (0.45) | TP53ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11818098 | 0.73 | NR4A2 (0.44) | TP53MAPTMEN1KMT2ALMNA | |
| SCHEMBL6911927 | 0.71 | TAAR1 (0.41) | ALDH1A1SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL27846387 | 0.70 | TP53 (0.50) | TP53ATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11815276 | 0.68 | KMT2A (0.51) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |