Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11828036 | 0.99 | KDM4E (0.43) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11510880 | 0.92 | MPO (0.48) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11824254 | 0.90 | MPO (0.49) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11822106 | 0.84 | MAPT (0.50) | KDM4EMAPTHTTPSEN1PSEN2 | |
| SCHEMBL11755867 | 0.84 | MAPT (0.65) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11828278 | 0.82 | ALDH1A1 (0.63) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11277311 | 0.80 | MAPT (0.68) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL6610203 | 0.78 | RAD52 (0.55) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11825503 | 0.77 | MAPT (0.55) | MEN1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL5446951 | 0.75 | RAD52 (0.42) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975398-A | INDICATOR FOR DETERMINATION OF GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-08-17 | — | — | US | claimed |
| US-3988208-A | FOR GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3975398-A | INDICATOR FOR DETERMINATION OF GLUCOSE | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-08-17 | — | — | US | disclosed |