Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | CPA1 | P15085 | 4/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835980 | 0.79 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11823662 | 0.78 | MMP12 (0.58) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11829069 | 0.77 | MMP12 (0.61) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL21012482 | 0.76 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11828178 | 0.75 | MMP12 (0.55) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11835988 | 0.74 | MEN1 (0.47) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11827662 | 0.73 | MMP12 (0.56) | SMN1; SMN2MMP12MMP2MMP9MMP13 | |
| SCHEMBL11829944 | 0.73 | MMP12 (0.52) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11835616 | 0.73 | MEN1 (0.58) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL11830559 | 0.71 | MMP12 (0.51) | MMP12MMP2MMP9MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |