Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26694103 | 0.78 | NPSR1 (0.47) | NPSR1ALDH1A1TSHRGFERLMNA | |
| SCHEMBL11825905 | 0.72 | ALDH1A1 (0.52) | NPSR1ALDH1A1TSHRCHRM2HTR1A | |
| SCHEMBL11822716 | 0.70 | KDM1A (0.60) | NPSR1ALDH1A1TSHRCHRM2HTR1A | |
| SCHEMBL11821877 | 0.69 | CYP2D6 (0.62) | NPSR1ALDH1A1TSHRCHRM2HTR1A | |
| SCHEMBL8140807 | 0.68 | LMNA (0.57) | NPSR1ALDH1A1TSHRALOX15LMNA | |
| SCHEMBL21169559 | 0.68 | TSHR (0.53) | NPSR1ALDH1A1TSHRCHRM1ALOX15 | |
| SCHEMBL10066394 | 0.67 | NPSR1 (0.63) | NPSR1ALDH1A1TSHRCHRM1ALOX15 | |
| SCHEMBL12963502 | 0.65 | NPSR1 (0.60) | NPSR1ALDH1A1TSHRCHRM1ALOX15 | |
| SCHEMBL6858952 | 0.65 | ALDH1A1 (0.53) | NPSR1ALDH1A1TSHRCHRM1ALOX15 | |
| SCHEMBL141530 | 0.64 | CHRM2 (0.62) | NPSR1ALDH1A1TSHRCHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |