SCHEMBL11825943

SCHEMBL11825943

COc1ccccc1Cc1nnc(-c2ccccc2C(=O)O)o1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.53
APLNR P35414 1/20 0.49
BRS3 P32247 1/20 0.48
PTK2 Q05397 2/20 0.46
PLAT P00750 1/20 0.45
RAB9A P51151 3/20 0.45
ALDH1A1 P00352 3/20 0.45
POLB P06746 2/20 0.45
KMT2A Q03164 1/20 0.45
CYP2C9 P11712 1/20 0.44
HIF1A Q16665 1/20 0.44
HPGD P15428 3/20 0.44
NPC1 O15118 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
THRB P10828 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HTT P42858 1/20 0.43
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11816118 0.82 NPC1 (0.62) EGFRAPLNRPTK2PLATRAB9A
SCHEMBL11615095 0.82 ALDH1A1 (0.58) EGFRRAB9AALDH1A1KMT2AHPGD
SCHEMBL11822985 0.81 RAB9A (0.67) EGFRBRS3PTK2RAB9AALDH1A1
SCHEMBL2440740 0.77 HPGD (0.52) EGFRAPLNRPTK2RAB9AALDH1A1
SCHEMBL27828121 0.76 CYP2C9 (0.55) BRS3ALDH1A1KMT2ACYP2C9HIF1A
SCHEMBL32674532 0.73 EGFR (0.52) EGFRRAB9AALDH1A1POLBKMT2A
SCHEMBL11341017 0.73 EGFR (0.52) EGFRRAB9AALDH1A1POLBKMT2A
SCHEMBL11611975 0.72 KDM4E (0.68) RAB9AALDH1A1POLBKMT2AHPGD
SCHEMBL11821519 0.71 EGFR (0.50) EGFRPOLBKMT2AHIF1ASMN1; SMN2
SCHEMBL536179 0.70 HTT (0.62) ALDH1A1KMT2AHPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3964896-A Oxadiazole benzoic acid derivatives as herbicides UNIROYAL, INC. (US) 1976-06-22 US disclosed