Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376707 | 0.92 | PRMT3 (0.45) | OPRL1KCNH2PRMT3CARM1PRMT6 | |
| SCHEMBL3436371 | 0.84 | SLC18A3 (0.61) | OPRL1KCNH2DRD2SLC6A4HTR2C | |
| SCHEMBL4747037 | 0.80 | DRD2 (0.76) | DRD2HTR2CDRD4 | |
| SCHEMBL13085385 | 0.79 | HTR2C (0.58) | OPRL1KCNH2HTR2CDRD4 | |
| SCHEMBL9323878 | 0.78 | SLC6A4 (0.74) | OPRL1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL13450177 | 0.77 | MEN1 (0.67) | OPRL1DRD2DRD4OPRM1 | |
| SCHEMBL3436370 | 0.77 | DRD4 (0.59) | OPRL1KCNH2DRD2HTR2CDRD4 | |
| SCHEMBL10276962 | 0.77 | HTR2C (0.47) | OPRL1KCNH2DRD2SLC6A4HTR2C | |
| SCHEMBL13999713 | 0.76 | HTR2C (0.47) | OPRL1KCNH2DRD2SLC6A4HTR2C | |
| SCHEMBL3554720 | 0.76 | DRD4 (0.52) | OPRL1KCNH2DRD2SLC6A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995045-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-11-30 | — | — | US | disclosed |