Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KHK | P50053 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836332 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11836494 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11821448 | 0.84 | MEN1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11823175 | 0.83 | MEN1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11821452 | 0.83 | MEN1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11833124 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL6949089 | 0.77 | MKNK1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11826283 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL11832860 | 0.76 | MGMT (0.50) | ALDH1A1KDM4EHPGDMAPK1MEN1 | |
| SCHEMBL11828440 | 0.74 | APAF1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |