Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832023 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TDP1PDCD1CD274CYP1A2 | |
| SCHEMBL11837592 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1PDCD1CD274CYP1A2 | |
| SCHEMBL27559990 | 0.81 | FFAR1 (0.53) | ALDH1A1TDP1PDCD1CD274FBP1 | |
| SCHEMBL3905288 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TDP1PDCD1CD274CYP1A2 | |
| SCHEMBL11829343 | 0.79 | CSNK2A1 (0.53) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL11830311 | 0.79 | MMP12 (0.42) | ALDH1A1PDCD1CD274MMP2MMP9 | |
| SCHEMBL11827993 | 0.79 | PPARG (0.50) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL101169 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1CRHBPCRHR2PTGES | |
| SCHEMBL15822786 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1PDCD1CD274CYP1A2 | |
| SCHEMBL98747 | 0.78 | TDP1 (0.53) | ALDH1A1TDP1PDCD1CD274CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |