Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826519 | 0.91 | BRD4 (0.39) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL11824806 | 0.84 | HPGD (0.43) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL11875313 | 0.83 | NPC1 (0.43) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL11670298 | 0.82 | EGFR (0.42) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL11670421 | 0.81 | NPC1 (0.46) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL7109250 | 0.80 | NPC1 (0.48) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL7610813 | 0.79 | MAOB (0.56) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL11820069 | 0.79 | ADRB2 (0.40) | BRD4MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL10917600 | 0.79 | NR4A2 (0.54) | HPGDNPC1RAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL11814470 | 0.79 | ABCB1 (0.52) | HPGDNPC1RAB9ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994974-A | BRONCHODILATORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |