Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826510 | 0.91 | HPGD (0.43) | BRD4MAPTMAPK1NPSR1HPGD | |
| SCHEMBL11824810 | 0.84 | FOLH1 (0.40) | BRD4HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11875315 | 0.84 | KMT2A (0.40) | BRD4MAPTHPGDNPC1RAB9A | |
| SCHEMBL11670418 | 0.81 | CYP19A1 (0.40) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11814480 | 0.79 | PDCD1 (0.48) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11875514 | 0.78 | EGFR (0.39) | HPGDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL11705297 | 0.77 | KMT2A (0.51) | MAPTRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11820069 | 0.77 | ADRB2 (0.40) | BRD4MAPTMAPK1NPSR1KMT2A | |
| Bromide SCHEMBL11705735 | 0.76 | KMT2A (0.50) | MAPTRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11766997 | 0.75 | KMT2A (0.56) | KMT2AMEN1SMPD1EGFRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994974-A | BRONCHODILATORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |