SCHEMBL11827353

SCHEMBL11827353

CCCCCC(C)C(C)(C)c1cc(O)cc(O)c1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 8/20 0.44
PTGS2 P35354 4/20 0.43
CYP3A4 P08684 1/20 0.43
CNR1 P21554 4/20 0.36
CNR2 P34972 4/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31545832 0.98 PTGS2 (0.44) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL31320348 0.83 ADRB2 (0.42) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL31544989 0.81 PTGS2 (0.46) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL31320383 0.81 PTGS2 (0.46) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL11795050 0.81 ESR1 (0.47) PTGS2CYP3A4
SCHEMBL31320421 0.81 PTGS2 (0.46) ADRB2PTGS2CYP3A4CNR1CNR2
Methoxymethane SCHEMBL11836609 0.80 PTGS2 (0.40) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL31320426 0.79 PTGS2 (0.40) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL31320366 0.79 PTGS2 (0.40) ADRB2PTGS2CYP3A4CNR1CNR2
SCHEMBL31320428 0.79 PTGS2 (0.40) ADRB2PTGS2CYP3A4CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3931232-A 3-Alkyl xanthene compounds SMITHKLINE CORPORATION (US) 1976-01-06 US disclosed