Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.46 |
| ▸ | CPA1 | P15085 | 4/20 | 0.46 |
| ▸ | MMP12 | P39900 | 6/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827741 | 0.87 | HCAR2 (0.43) | MME | |
| SCHEMBL11828127 | 0.82 | MMP12 (0.51) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11830248 | 0.80 | MMP12 (0.49) | MMEACEACE2CPA1MMP12 | |
| Ethane SCHEMBL11827654 | 0.80 | MMP12 (0.49) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11832469 | 0.79 | MMP12 (0.51) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11829687 | 0.79 | MMP12 (0.51) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11827868 | 0.79 | MMP12 (0.46) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11830083 | 0.79 | MMP12 (0.54) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11827382 | 0.78 | MMP12 (0.50) | MMEACEACE2CPA1MMP12 | |
| SCHEMBL11830295 | 0.77 | MMP12 (0.49) | MMEACEACE2CPA1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |