Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827638 | 0.87 | MME (0.51) | MME | |
| SCHEMBL11823509 | 0.85 | MAOB (0.45) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11831427 | 0.85 | MAOB (0.47) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11828270 | 0.84 | MAOB (0.42) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| Alcohol SCHEMBL11826938 | 0.83 | MAOB (0.46) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11830406 | 0.83 | HCAR2 (0.44) | HCAR2MAOBMMEPPARGBRS3 | |
| Ethane SCHEMBL11827755 | 0.83 | MAOB (0.48) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11829318 | 0.82 | MAOB (0.50) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11822596 | 0.82 | MAOB (0.42) | HCAR2MAOBITGB1ITGA4ITGB7 | |
| SCHEMBL11829300 | 0.82 | MAOB (0.49) | HCAR2MAOBITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |