Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830747 | 0.80 | SLC13A5 (0.50) | CYP2D6ACACBGSK3BALDH1A1MAPT | |
| SCHEMBL12733163 | 0.77 | LMNA (0.52) | GSK3BALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL8366739 | 0.76 | ACACB (0.51) | ACACBGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL3899096 | 0.76 | ACACB (0.51) | ACACBGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL7051006 | 0.76 | ACACB (0.51) | ACACBGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL102286 | 0.76 | ALDH1A1 (0.58) | ACACBALDH1A1MAPTKDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL20640262 | 0.75 | MAPT (0.50) | GSK3BALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL12733172 | 0.75 | GSK3B (0.47) | ACACBGSK3BALDH1A1MAPTKDM4E | |
| SCHEMBL15752588 | 0.74 | ACACB (0.46) | CYP2D6ACACBGSK3BALDH1A1MAPT | |
| SCHEMBL27777300 | 0.73 | ALDH1A1 (0.51) | ACACBALDH1A1MAPTKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |