Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833487 | 0.85 | MME (0.44) | MMEEPHX2MAOBKDM4EALDH1A1 | |
| SCHEMBL11844624 | 0.80 | MME (0.46) | MMEEPHX2MAOBKDM4EALDH1A1 | |
| SCHEMBL11834108 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL11829151 | 0.80 | ALDH1A1 (0.42) | EPHX2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11824134 | 0.79 | MAOB (0.48) | MMEEPHX2MAOBKDM4EALDH1A1 | |
| SCHEMBL11836185 | 0.78 | GRM6 (0.42) | MAOBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11824437 | 0.76 | MAOB (0.48) | MMEEPHX2MAOBKDM4EALDH1A1 | |
| SCHEMBL11839428 | 0.76 | MAPT (0.49) | MAOBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11827746 | 0.75 | MAOB (0.47) | MMEEPHX2MAOBKDM4EALDH1A1 | |
| SCHEMBL11823591 | 0.75 | MAOB (0.47) | MMEEPHX2MAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |