Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824009 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11836347 | 0.81 | NPC1 (0.49) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL5924878 | 0.80 | F2RL3 (0.53) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11834108 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11828428 | 0.80 | MME (0.44) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11837594 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11836185 | 0.77 | GRM6 (0.42) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11790207 | 0.77 | CASP1 (0.47) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11837196 | 0.76 | GRM6 (0.41) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL11842029 | 0.76 | GRM6 (0.41) | ALDH1A1KDM4EMAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |