Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824134 | 0.82 | MAOB (0.48) | MAOBHCAR2KDM4EALDH1A1TNF | |
| SCHEMBL11824437 | 0.82 | MAOB (0.48) | MAOBHCAR2KDM4EALDH1A1TNF | |
| SCHEMBL11828131 | 0.81 | MAOB (0.50) | MAOBHCAR2KDM4EALDH1A1TNF | |
| SCHEMBL11827746 | 0.81 | MAOB (0.47) | MAOBHCAR2KDM4EALDH1A1TNF | |
| SCHEMBL11823591 | 0.81 | MAOB (0.47) | MAOBHCAR2KDM4EALDH1A1TNF | |
| SCHEMBL11839776 | 0.79 | PGR (0.40) | KDM4EALDH1A1TNFLMNAHSP90AA1 | |
| SCHEMBL11830154 | 0.77 | MAOB (0.48) | MAOBHCAR2MAPTMMESMN1; SMN2 | |
| SCHEMBL11826267 | 0.76 | MAOB (0.49) | MAOBHCAR2FFAR1MME | |
| SCHEMBL11837690 | 0.76 | MAOB (0.41) | MAOBHCAR2KDM4EALDH1A1TNF | |
| SCHEMBL11830204 | 0.76 | MAOB (0.41) | MAOBHCAR2KDM4EALDH1A1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |